Research

Trainees & Research Emphasis - Faculty

At least twelve months are devoted primarily for research activities, and as much time as possible is taken during clinical time to expand upon the research experience.

Each Fellow, under the guidance of a faculty advisor, chooses a research opportunity from the ongoing laboratory and clinical research programs in operation within the division.

gastroenterology researcher Major focus of research include:

  • Translational research
  • Chronic liver disease
  • Parenteral/enteral nutrition
  • Chronic viral hepatitis
  • Colorectal cancer
  • Inflammatory Bowel Disease

Specific Research Techniques:

  • Molecular biology
  • Immunologic assays
  • Biochemical analysis-all laboratory based.
  • Endoscopic specialties-ERCP (diagnostic and therapeutic)
  • EUS
  • Motility
  • Video Capsule Endoscopy
     

Representative Funded Research Projects in GI

Racial Disparity in Colorectal Cancer: Molecular Mechanisms (1R21CA175916-01) 
PI: Adhip N. Majumdar, Co-PI Fadi Antaki.

Screening an Urban Population for NASH associated LAL(lysosomal acid lipase) Deficiency-Comparison of Caucasian and African Americans
PI Milton Mutchnick, Co-PI Paul Naylor Funding: Synageva BioPharma Corp

Hepatocellular Carcinoma Development in African Americans with Hepatitis Infection (IN-US-334-1749)
PI Milton Mutchnick, Co-PI Paul Naylor Funding: Gilead Sciences

Racial Disparity in Hepatitis B Treatment Responses to Anti-virals: A Proposal to Gather Data Comparing African Americans vs Non African Americans 
PI Milton Mutchnick, Co-PI Paul Naylor Funding: Gilead Sciences

Racial Diversity in Demographics, Outcomes and Treatment of Intrahepatic Cholestatic Liver disease
PI Milton Mutchnick, Co-PI Paul Naylor Funding: Intercept Pharma

Safety of Endoscopic Resection of Large Colorectal Polyps: A Randomized Trial. 
Fadi Antaki Co-Investigator and site PI Funding: Boston Scientific Corporation

Colonoscopy vs. Fecal Immunochemical Test in Reducing Mortality from Colorectal Cancer (CONFIRM)
VA Cooperative PI: D. Robertson & J. Dominitz ; Co-PI and site PI Fadi Antaki

Evaluation of Wirelessly Observed Therapy to Optimize Adherence in Patients with Hepatitis C and Increased Risk for Nonadherence to Treatment
PI Milton Mutchnick, Co-PI Paul Naylor Funding: Proteus Digital Technology